Polymorphisms in Glyoxalase I Gene Are Not Associated with Glyoxalase I Expression in Whole Blood or Markers of Methylglyoxal Stress: The CODAM Study

Polymorphisms in Glyoxalase I Gene Are Not Associated with Glyoxalase I Expression in Whole Blood or Markers of Methylglyoxal Stress: The CODAM Study

Glyoxalase 1 (Glo1) is the rate-limiting enzyme in the detoxification of methylglyoxal (MGO) into D-lactate. MGO is a major precursor of advanced glycation endproducts (AGEs), and both are associated with development of age-related diseases. Since genetic variation in <i>GLO1</i> may alt...

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Main Authors: Kim Maasen (Author), Nordin M. J. Hanssen (Author), Carla J. H. van der Kallen (Author), Coen D. A. Stehouwer (Author), Marleen M. J. van Greevenbroek (Author), Casper G. Schalkwijk (Author)
Format: Book
Published: MDPI AG, 2021-02-01T00:00:00Z.
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3rd Floor Main Library

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