Long-term potentiation in spinal nociceptive pathways as a novel target for pain therapy

• Main Authors: Liu Xian-Guo (Author), Drdla Ruth (Author), Wilder-Smith Oliver (Author), Ruscheweyh Ruth (Author), Sandkühler Jürgen (Author)
• Format: Book
• Published: SAGE Publishing, 2011-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Long-term potentiation (LTP) in nociceptive spinal pathways shares several features with hyperalgesia and has been proposed to be a cellular mechanism of pain amplification in acute and chronic pain states. Spinal LTP is typically induced by noxious input and has...