The Effect of Antioxidant on Development of Fibrosis by Cisplatin in Rats

• Main Authors: Yoshiko Kawai (Author), Tomohiko Satoh (Author), Daisuke Hibi (Author), Yukihiro Ohno (Author), Yuka Kohda (Author), Katsuyuki Miura (Author), Munekazu Gemba (Author)
• Format: Book
• Published: Elsevier, 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cisplatin causes chronic interstitial disease with fibrosis, but the development mechanism of interstitial fibrosis is not yet understood. We examined the effect of an antioxidant, N,N'-diphenyl-1,4-phenylenediamine (DPPD), on development of interstitial fibrosis induced by cisplatin. Cisplatin...