Rapamycin Protects Against High Fat Diet-Induced Obesity in C57BL/6J Mice

• Main Authors: Geng-Ruei Chang (Author), Yi-Shin Chiu (Author), Ying-Ying Wu (Author), Wen-Ying Chen (Author), Jiunn-Wang Liao (Author), Te-Hsin Chao (Author), Frank Chiahung Mao (Author)
• Format: Book
• Published: Elsevier, 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rapamycin (RAPA), an immunosuprpressive drug used extensively to prevent graft rejection in transplant patients, has been reported to inhibit adipogenesis in vitro. In this study, we investigated the anti-obesity effects of RAPA in C57BL/6J mice on a high-fat diet (HFD). Mice treated with RAPA (2 mg...