Inhibition of ACOX1 enhances the therapeutic efficacy of obeticholic acid in treating non-alcoholic fatty liver disease and mitigates its lipotoxicity
Background and aims:High-dose Obeticholic acid exhibits promise for non-alcoholic fatty liver disease (NAFLD) treatment but can induce lipotoxicity. Our study sought to understand this mechanism and propose a solution.Approach and Results:In a non-alcoholic fatty liver disease (NAFLD) model induced...
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| Main Authors: | , , , , , , |
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| Format: | Book |
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Frontiers Media S.A.,
2024-03-01T00:00:00Z.
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