Attenuation of Red Blood Cell Storage Lesions with Vitamin C

• Main Authors: Kimberly Sanford (Author), Bernard J. Fisher (Author), Evan Fowler (Author), Alpha A. Fowler (Author), Ramesh Natarajan (Author)
• Format: Book
• Published: MDPI AG, 2017-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Stored red blood cells (RBCs) undergo oxidative stress that induces deleterious metabolic, structural, biochemical, and molecular changes collectively referred to as "storage lesions". We hypothesized that vitamin C (VitC, reduced or oxidized) would reduce red cell storage lesions, thus pr...