Chemotherapy impairs skeletal muscle mitochondrial homeostasis in early breast cancer patients

• Main Authors: Joris Mallard (Author), Elyse Hucteau (Author), Anne‐Laure Charles (Author), Laura Bender (Author), Claire Baeza (Author), Mathilde Pélissie (Author), Philippe Trensz (Author), Carole Pflumio (Author), Michal Kalish‐Weindling (Author), Bernard Gény (Author), Roland Schott (Author), Fabrice Favret (Author), Xavier Pivot (Author), Thomas J. Hureau (Author), Allan F. Pagano (Author)
• Format: Book
• Published: Wiley, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Chemotherapy is extensively used to treat breast cancer and is associated with skeletal muscle deconditioning, which is known to reduce patients' quality of life, treatment efficiency, and overall survival. To date, skeletal muscle mitochondrial alterations represent a major...