Increased levels of HE4 (WFDC2) in systemic sclerosis: a novel biomarker reflecting interstitial lung disease severity?

• Автори: Mingxia Zhang (Автор), Liyun Zhang (Автор), Linning E (Автор), Ke Xu (Автор), Xu Fei Wang (Автор), Bin Zhang (Автор), Jie Su (Автор), Zemin Meng (Автор)
• Формат: Книга
• Опубліковано: SAGE Publishing, 2020-09-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Background: Human epididymis protein 4 (HE4, also known as WFDC-2) has been implicated in fibrotic disorders pathobiology. We tested the hypothesis that HE4 may be used as a candidate biomarker for systemic sclerosis (SSc)-related interstitial lung disease (SSc-ILD). Methods: A total of 169 consecut...