The Current State and Future of CRISPR-Cas9 gRNA Design Tools

Recent years have seen the development of computational tools to assist researchers in performing CRISPR-Cas9 experiment optimally. More specifically, these tools aim to maximize on-target activity (guide efficiency) while also minimizing potential off-target effects (guide specificity) by analyzing...

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Autores principales: Laurence O. W. Wilson (Autor), Aidan R. O'Brien (Autor), Denis C. Bauer (Autor)
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Publicado: Frontiers Media S.A., 2018-07-01T00:00:00Z.
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