Therapeutic Potential of Astragaloside IV Against Adriamycin-Induced Renal Damage in Rats via Ferroptosis

• Main Authors: Lu-Yun Qin (Author), Peng Guan (Author), Jian-Xin Wang (Author), Yu Chen (Author), Ya-Shuo Zhao (Author), Sheng-Chang Yang (Author), Ya-Jing Guo (Author), Na Wang (Author), En-Sheng Ji (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Adriamycin (ADR) has been utilized to treat cancer for several decades. However, ADR-induced renal injury is one of the most common side effects accompanying ADR therapy. In the present study, we revealed that astragaloside IV (ASIV) was beneficial for renal injury caused by Adriamycin. We demonstra...