Novel benzoylurea derivative decreases TRPM7 channel function and inhibits cancer cells migration

• Main Authors: Xiaoding Zhang (Author), Rui Zong (Author), Yu Han (Author), Xiaoming Li (Author), Shuangyu Liu (Author), Yixue Cao (Author), Nan Jiang (Author), Pingping Chen (Author), Haixia Gao (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The transient receptor potential melastatin 7 channel (TRPM7) is a nonselective cation channel highly expressed in some human cancer tissues. TRPM7 is involved in the proliferation, migration, invasion, and epithelial-mesenchymal transition (EMT) of cancer cells. Modulation of TRPM7 could be a promi...