Methotrexate-related adverse events and impact of concomitant treatment with folic acid and tumor necrosis factor-alpha inhibitors: An assessment using the FDA adverse event reporting system

• Auteurs principaux: Kenji Onda (Auteur), Takeshi Honma (Auteur), Koichi Masuyama (Auteur)
• Format: Livre
• Publié: Frontiers Media S.A., 2023-02-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Methotrexate (MTX) is an essential anti-rheumatic drug used to treat rheumatoid arthritis (RA). Prevention or management of adverse reactions, including interstitial lung disease (ILD), hepatotoxicity, myelosuppression, and infection, remains fundamental for safe MTX therapy. Using the Food and Drug...