A novel SIRT6 activator ameliorates neuroinflammation and ischemic brain injury via EZH2/FOXC1 axis

• Main Authors: Tailin He (Author), Jialin Shang (Author), Chenglong Gao (Author), Xin Guan (Author), Yingyi Chen (Author), Liwen Zhu (Author), Luyong Zhang (Author), Cunjin Zhang (Author), Jian Zhang (Author), Tao Pang (Author)
• Format: Book
• Published: Elsevier, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ischemic stroke is the second leading cause of death worldwide with limited medications and neuroinflammation was recognized as a critical player in the progression of stroke, but how to control the overactive neuroinflammation is still a long-standing challenge. Here, we designed a novel SIRT6 acti...