Assessing immune hepatotoxicity of troglitazone with a versatile liver-immune-microphysiological-system

• Main Authors: Quanfeng Deng (Author), Youlong Yang (Author), Yuangui Liu (Author), Mengting Zou (Author), Guiyuan Huang (Author), Shiqi Yang (Author), Lingyu Li (Author), Yueyang Qu (Author), Yong Luo (Author), Xiuli Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Drug-induced liver injury is a prevalent adverse event associated with pharmaceutical agents. More significantly, there are certain drugs that present severe hepatotoxicity only during the clinical phase, consequently leading to the termination of drug development during clinical trials or the withd...