Mineralocorticoid Receptor Antagonists in Diabetic Kidney Disease

• Main Authors: Daiji Kawanami (Author), Yuichi Takashi (Author), Yoshimi Muta (Author), Naoki Oda (Author), Dai Nagata (Author), Hiroyuki Takahashi (Author), Makito Tanabe (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diabetic kidney disease (DKD) is a major cause of end-stage kidney disease (ESKD) worldwide. Mineralocorticoid receptor (MR) plays an important role in the development of DKD. A series of preclinical studies revealed that MR is overactivated under diabetic conditions, resulting in promoting inflamma...