Peptidomic Analysis of Skin Secretions of the Caribbean Frogs <i>Leptodactylus insularum</i> and <i>Leptodactylus nesiotus</i> (Leptodactylidae) Identifies an Ocellatin with Broad Spectrum Antimicrobial Activity

• Main Authors: Gervonne Barran (Author), Jolanta Kolodziejek (Author), Laurent Coquet (Author), Jérôme Leprince (Author), Thierry Jouenne (Author), Norbert Nowotny (Author), J. Michael Conlon (Author), Milena Mechkarska (Author)
• Format: Book
• Published: MDPI AG, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ocellatins are peptides produced in the skins of frogs belonging to the genus <i>Leptodactylus</i> that generally display weak antimicrobial activity against Gram-negative bacteria only. Peptidomic analysis of norepinephrine-stimulated skin secretions from <i>Leptodactylus insularu...