Antibodies to the Vi capsule of Salmonella Typhi in the serum of typhoid patients and healthy control subjects from a typhoid endemic region

• Main Author: Deborah House1,2, Vo A. Ho4,To S. Diep5, Nguyen T. Chinh6, Phan V. Bay4, Ha Vinh5, Minh Duc4, Christopher M. Parry2,3, Gordon Dougan1, Nicholas J. White2,3, Jeremy J. Farrar2,3, Tran Tinh Hien5, John Wain2,3 (Author)
• Format: Book
• Published: The Journal of Infection in Developing Countries, 2008-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: There is very little published data on the antibody response to the Vi capsular polysaccharide (Vi-CPS) of S. Typhi during naturally acquired typhoid fever in an endemic area.Methodology: An indirect ELISA, using tyraminated, purified Vi-CPS, was used to assay anti-Vi-CPS antibodies from...