Changes in the process of alternative RNA splicing results in soluble B and T lymphocyte attenuator with biological and clinical implications in critical illness

Changes in the process of alternative RNA splicing results in soluble B and T lymphocyte attenuator with biological and clinical implications in critical illness

Abstract Background Critically ill patients with sepsis and acute respiratory distress syndrome have severely altered physiology and immune system modifications. RNA splicing is a basic molecular mechanism influenced by physiologic alterations. Immune checkpoint inhibitors, such as B and T Lymphocyt...

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Main Authors: Sean F. Monaghan (Author), Debasree Banerjee (Author), Chun-Shiang Chung (Author), Joanne Lomas-Neira (Author), Kamil J. Cygan (Author), Christy L. Rhine (Author), William G. Fairbrother (Author), Daithi S. Heffernan (Author), Mitchell M. Levy (Author), William G. Cioffi (Author), Alfred Ayala (Author)
Format: Book
Published: BMC, 2018-06-01T00:00:00Z.
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