Neuronal modulation of brown adipose activity through perturbation of white adipocyte lipogenesis

• Main Authors: Adilson Guilherme (Author), David J. Pedersen (Author), Felipe Henriques (Author), Alexander H. Bedard (Author), Elizabeth Henchey (Author), Mark Kelly (Author), Donald A. Morgan (Author), Kamal Rahmouni (Author), Michael P. Czech (Author)
• Format: Book
• Published: Elsevier, 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Crosstalk between adipocytes and local neurons may be an important regulatory mechanism to control energy homeostasis. We previously reported that perturbation of adipocyte de novo lipogenesis (DNL) by deletion of fatty acid synthase (FASN) expands sympathetic neurons within white adipose...