Heterogenous loss of mismatch repair (MMR) protein expression: a challenge for immunohistochemical interpretation and microsatellite instability (MSI) evaluation

Heterogenous loss of mismatch repair (MMR) protein expression: a challenge for immunohistochemical interpretation and microsatellite instability (MSI) evaluation

Abstract Immunohistochemistry (IHC) for mismatch repair (MMR) proteins is used to identify MMR status: being diffusely positive (intact/retained nuclear staining) or showing loss of nuclear tumour staining (MMR protein deficient). Four colonic adenocarcinomas and a gastric adenocarcinoma with associ...

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Main Authors: Aoife J McCarthy (Author), Jose‐Mario Capo‐Chichi (Author), Tara Spence (Author), Sylvie Grenier (Author), Tracy Stockley (Author), Suzanne Kamel‐Reid (Author), Stefano Serra (Author), Peter Sabatini (Author), Runjan Chetty (Author)
Format: Book
Published: Wiley, 2019-04-01T00:00:00Z.
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3rd Floor Main Library

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