Altered pancreatic islet morphology and function in SGLT1 knockout mice on a glucose-deficient, fat-enriched diet

• Główni autorzy: Markus Mühlemann (Autor), Daniela Zdzieblo (Autor), Alexandra Friedrich (Autor), Constantin Berger (Autor), Christoph Otto (Autor), Heike Walles (Autor), Hermann Koepsell (Autor), Marco Metzger (Autor)
• Format: Książka
• Wydane: Elsevier, 2018-07-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Objectives: Glycemic control by medical treatment represents one therapeutic strategy for diabetic patients. The Na+-d-glucose cotransporter 1 (SGLT1) is currently of high interest in this context. SGLT1 is known to mediate glucose absorption and incretin secretion in the small intestine. Recently,...