Preventive effect of curcumin and its highly bioavailable preparation on hearing loss induced by single or repeated exposure to noise: A comparative and mechanistic study

• Autori principali: Taro Yamaguchi (Autore), Masanori Yoneyama (Autore), Yusuke Onaka (Autore), Atsushi Imaizumi (Autore), Kiyokazu Ogita (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2017-08-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

We sought to determine the preventive effects of curcumin and its highly bioavailable preparation on noise-induced hearing loss in a novel murine model of permanent hearing loss developed by repeated exposure to noise. Upon exposure to noise (8-kHz octave band noise, 90 dB sound pressure level, 1 h)...