Apolipoprotein E deficiency accelerates atherosclerosis development in miniature pigs

• Main Authors: Bin Fang (Author), Xueyang Ren (Author), Ying Wang (Author), Ze Li (Author), Lihua Zhao (Author), Manling Zhang (Author), Chu Li (Author), Zhengwei Zhang (Author), Lei Chen (Author), Xiaoxue Li (Author), Jiying Liu (Author), Qiang Xiong (Author), Lining Zhang (Author), Yong Jin (Author), Xiaorui Liu (Author), Lin Li (Author), Hong Wei (Author), Haiyuan Yang (Author), Rongfeng Li (Author), Yifan Dai (Author)
• Format: Book
• Published: The Company of Biologists, 2018-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Miniature pigs have advantages over rodents in modeling atherosclerosis because their cardiovascular system and physiology are similar to that of humans. Apolipoprotein E (ApoE) deficiency has long been implicated in cardiovascular disease in humans. To establish an improved large animal model of fa...