Multivariate Data Analysis and Central Composite Design-Oriented Optimization of Solid Carriers for Formulation of Curcumin-Loaded Solid SNEDDS: Dissolution and Bioavailability Assessment

• Main Authors: Leander Corrie (Author), Jaskiran Kaur (Author), Ankit Awasthi (Author), Sukriti Vishwas (Author), Monica Gulati (Author), Sumant Saini (Author), Bimlesh Kumar (Author), Narendra Kumar Pandey (Author), Gaurav Gupta (Author), Harish Dureja (Author), Dinesh Kumar Chellapan (Author), Kamal Dua (Author), Devesh Tewari (Author), Sachin Kumar Singh (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The study was initiated with two major purposes: investigating the role of isomalt (GIQ9) as a pharmaceutical carrier for solid self-nanoemulsifying drug delivery systems (S-SNEDDSs) and improving the oral bioavailability of lipophilic curcumin (CUN). GIQ9 has never been explored for solidification...