Galactosylated Polymer/Gold Nanorods Nanocomposites for Sustained and Pulsed Chemo-Photothermal Treatments of Hepatocarcinoma

• Main Authors: Gaetano Giammona (Author), Salvatore Emanuele Drago (Author), Giovanna Calabrese (Author), Paola Varvarà (Author), Maria Giovanna Rizzo (Author), Nicolò Mauro (Author), Giuseppe Nicotra (Author), Sabrina Conoci (Author), Giovanna Pitarresi (Author)
• Format: Book
• Published: MDPI AG, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this paper, we propose a rational design of a hybrid nanosystem capable of locally delivering a high amount of hydrophobic anticancer drugs (sorafenib or lenvatinib) and heat (hyperthermia) in a remote-controlled manner. We combined in a unique nanosystem the excellent NIR photothermal conversion...