Peroxisome proliferator-activated receptor alpha acts as a mediator of endoplasmic reticulum stress-induced hepatocyte apoptosis in acute liver failure

• Main Authors: Li Zhang (Author), Feng Ren (Author), Xiangying Zhang (Author), Xinxin Wang (Author), Hongbo Shi (Author), Li Zhou (Author), Sujun Zheng (Author), Yu Chen (Author), Dexi Chen (Author), Liying Li (Author), Caiyan Zhao (Author), Zhongping Duan (Author)
• Format: Book
• Published: The Company of Biologists, 2016-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Peroxisome proliferator-activated receptor α (PPARα) is a key regulator to ameliorate liver injury in cases of acute liver failure (ALF). However, its regulatory mechanisms remain largely undetermined. Endoplasmic reticulum stress (ER stress) plays an important role in a number of liver diseases. Th...