Novel copy number variations within SYCE1 caused meiotic arrest and non-obstructive azoospermia

• Main Authors: Yuhua Huang (Author), Ruhui Tian (Author), Junwei Xu (Author), Zhiyong Ji (Author), Yuxiang Zhang (Author), Liangyu Zhao (Author), Chao Yang (Author), Peng Li (Author), Erlei Zhi (Author), Haowei Bai (Author), Sha Han (Author), Jiaqiang Luo (Author), Jingpeng Zhao (Author), Jing Zhang (Author), Zhi Zhou (Author), Zheng Li (Author), Chencheng Yao (Author)
• Format: Book
• Published: BMC, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Non-obstructive azoospermia (NOA) is the most severe disease in male infertility, but the genetic causes for majority of NOA remain unknown. Methods Two Chinese NOA-affected patients were recruited to identify the genetic causal factor of infertility. Whole-exome sequencing (WES)...