Insulin Promotes the Proliferation of Human Umbilical Cord Matrix-Derived Mesenchymal Stem Cells by Activating the Akt-Cyclin D1 Axis

• Main Authors: Peng Li (Author), Jinsong Wei (Author), Xiang Gao (Author), Bo Wei (Author), Hao Lin (Author), Rui Huang (Author), Yanru Niu (Author), Kyu Lim (Author), Kaipeng Jing (Author), Jiaqi Chu (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. The functions of insulin in mesenchymal stem cells (MSC) remain poorly understood. Methods. MSC from human umbilical cord matrix (UCM) cultured in serum-free media (SFM) with or without insulin were subjected to various molecular biological analyses to determine their proliferation and g...