Establishment of multiplex RT-PCR to detect fusion genes for the diagnosis of Ewing sarcoma

• Главные авторы: Hitomi Ueno-Yokohata (Автор), Hajime Okita (Автор), Keiko Nakasato (Автор), Chikako Kiyotani (Автор), Motohiro Kato (Автор), Kimikazu Matsumoto (Автор), Nobutaka Kiyokawa (Автор), Atsuko Nakazawa (Автор), Takako Yoshioka (Автор)
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• Опубликовано: BMC, 2021-11-01T00:00:00Z.
• Предметы: article
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Abstract Background Detection of the tumor-specific EWSR1/FUS-ETS fusion gene is essential to diagnose Ewing sarcoma. Reverse transcription-polymerase chain reaction (RT-PCR) and fluorescence in situ hybridization are commonly used to detect the fusion gene, and assays using next-generation sequenci...