Activation of sigma-1 receptor chaperone in the treatment of neuropsychiatric diseases and its clinical implication
Endoplasmic reticulum (ER) protein sigma-1 receptor represents unique chaperone activity in the central nervous system, and it exerts a potent influence on a number of neurotransmitter systems. Several lines of evidence suggest that activation of sigma-1 receptor plays a role in the pathophysiology...
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Elsevier,
2015-01-01T00:00:00Z.
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