Thiopurine S-methyltransferase and Pemphigus Vulgaris: A Phenotype-Genotype Study

• প্রধান লেখক: Maral Mokhtari (লেখক), Farzaneh Mostanbet (লেখক), Saideh Nekooee Fard (লেখক), Golsa Shekarkhar (লেখক), Mozhdeh Sepaskhah (লেখক), Maryam Sadat Sadati (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Iranian Society of Pathology, 2020-10-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Background & Objective:  Thiopurine drugs are considered as a treatment modality in various autoimmune disorders including pemphigus vulgaris (PV). These drugs are metabolized by an enzyme "Thiopurine S-methyl transferase" (TPMT). Various variants of this enzyme may have decreased acti...