Thiopurine S-methyltransferase and Pemphigus Vulgaris: A Phenotype-Genotype Study

• Autors principals: Maral Mokhtari (Autor), Farzaneh Mostanbet (Autor), Saideh Nekooee Fard (Autor), Golsa Shekarkhar (Autor), Mozhdeh Sepaskhah (Autor), Maryam Sadat Sadati (Autor)
• Format: Llibre
• Publicat: Iranian Society of Pathology, 2020-10-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Background & Objective:  Thiopurine drugs are considered as a treatment modality in various autoimmune disorders including pemphigus vulgaris (PV). These drugs are metabolized by an enzyme "Thiopurine S-methyl transferase" (TPMT). Various variants of this enzyme may have decreased acti...