Thiopurine S-methyltransferase and Pemphigus Vulgaris: A Phenotype-Genotype Study

• Κύριοι συγγραφείς: Maral Mokhtari (Συγγραφέας), Farzaneh Mostanbet (Συγγραφέας), Saideh Nekooee Fard (Συγγραφέας), Golsa Shekarkhar (Συγγραφέας), Mozhdeh Sepaskhah (Συγγραφέας), Maryam Sadat Sadati (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Iranian Society of Pathology, 2020-10-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Background & Objective:  Thiopurine drugs are considered as a treatment modality in various autoimmune disorders including pemphigus vulgaris (PV). These drugs are metabolized by an enzyme "Thiopurine S-methyl transferase" (TPMT). Various variants of this enzyme may have decreased acti...