Thiopurine S-methyltransferase and Pemphigus Vulgaris: A Phenotype-Genotype Study

• Päätekijät: Maral Mokhtari (Tekijä), Farzaneh Mostanbet (Tekijä), Saideh Nekooee Fard (Tekijä), Golsa Shekarkhar (Tekijä), Mozhdeh Sepaskhah (Tekijä), Maryam Sadat Sadati (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Iranian Society of Pathology, 2020-10-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Background & Objective:  Thiopurine drugs are considered as a treatment modality in various autoimmune disorders including pemphigus vulgaris (PV). These drugs are metabolized by an enzyme "Thiopurine S-methyl transferase" (TPMT). Various variants of this enzyme may have decreased acti...