Thiopurine S-methyltransferase and Pemphigus Vulgaris: A Phenotype-Genotype Study

• Những tác giả chính: Maral Mokhtari (Tác giả), Farzaneh Mostanbet (Tác giả), Saideh Nekooee Fard (Tác giả), Golsa Shekarkhar (Tác giả), Mozhdeh Sepaskhah (Tác giả), Maryam Sadat Sadati (Tác giả)
• Định dạng: Sách
• Được phát hành: Iranian Society of Pathology, 2020-10-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Background & Objective:  Thiopurine drugs are considered as a treatment modality in various autoimmune disorders including pemphigus vulgaris (PV). These drugs are metabolized by an enzyme "Thiopurine S-methyl transferase" (TPMT). Various variants of this enzyme may have decreased acti...