Evaluation of physicochemical and microbiological stability of liquid preparation from tizanidine hydrochloride tablets - a Hospital concern

• Main Authors: Caren Gobetti (Author), Andressa da Silva Bitencourt (Author), Márcio Vinícius Ayres (Author), Ana Lucia Peixoto de Freitas (Author), Andreas Sebastian Loureiro Mendez (Author), Cássia Virginia Garcia (Author)
• Format: Book
• Published: Universidade de São Paulo, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tizanidine hydrochloride is a centrally acting skeletal muscle relaxant, used in the management of spasticity. This drug is commercially available only as tablets, which highlights the need to develop oral liquid formulations. In the hospital environment, this aspect is circumvented by the preparati...