Metabolomics to unveil and understand phenotypic diversity between pathogen populations.

• Main Authors: Ruben t'Kindt (Author), Richard A Scheltema (Author), Andris Jankevics (Author), Kirstyn Brunker (Author), Suman Rijal (Author), Jean-Claude Dujardin (Author), Rainer Breitling (Author), David G Watson (Author), Graham H Coombs (Author), Saskia Decuypere (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Leishmaniasis is a debilitating disease caused by the parasite Leishmania. There is extensive clinical polymorphism, including variable responsiveness to treatment. We study Leishmania donovani parasites isolated from visceral leishmaniasis patients in Nepal that responded differently to antimonial...