Conjugation of Mannans to Enhance the Potency of Liposome Nanoparticles for the Delivery of RNA Vaccines

• Главные авторы: Roshan Goswami (Автор), Derek T. O'Hagan (Автор), Roberto Adamo (Автор), Barbara C. Baudner (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2021-02-01T00:00:00Z.
• Предметы: article
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Recent approval of mRNA vaccines to combat COVID-19 have highlighted the potential of this platform. Lipid nanoparticles (LNP) is the delivery vehicle of choice for mRNA as they prevent its enzymatic degradation by encapsulation. We have recently shown that surface exposition of mannose, incorporate...