Overexpression of FTO inhibits excessive proliferation and promotes the apoptosis of human glomerular mesangial cells by alleviating FOXO6 m6A modification via YTHDF3-dependent mechanisms

Background: N6-methyladenosine (m6A) is a prevalent post-transcriptional modification presented in messenger RNA (mRNA) of eukaryotic organisms. Chronic glomerulonephritis (CGN) is characterised by excessive proliferation and insufficient apoptosis of human glomerular mesangial cells (HGMCs) but its...

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Main Authors: Xingxing Zhuang (Author), Tao Liu (Author), Liangbing Wei (Author), Jiarong Gao (Author)
Format: Book
Published: Frontiers Media S.A., 2023-09-01T00:00:00Z.
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3rd Floor Main Library

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