Puerarin Restores Autophagosome-Lysosome Fusion to Alleviate Cadmium-Induced Autophagy Blockade via Restoring the Expression of Rab7 in Hepatocytes

• Hoofdauteurs: Tao Wang (Auteur), Li Wang (Auteur), Yi Zhang (Auteur), Jian Sun (Auteur), Yilin Xie (Auteur), Yan Yuan (Auteur), Jianhong Gu (Auteur), Jianchun Bian (Auteur), Zongping Liu (Auteur), Hui Zou (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Autophagic dysfunction is one of the main mechanisms by which the environmental pollutant cadmium (Cd) induces cell injury. Puerarin (Pue, a monomeric Chinese herbal medicine extract) has been reported to alleviate Cd-induced cell injury by regulating autophagy pathways; however, its detailed mechan...