Beyond Adherence Thresholds: A Simulation Study of the Optimal Classification of Longitudinal Adherence Trajectories From Medication Refill Histories

• Những tác giả chính: Samuel S. Allemann (Tác giả), Dan Dediu (Tác giả), Alexandra Lelia Dima (Tác giả)
• Định dạng: Sách
• Được phát hành: Frontiers Media S.A., 2019-04-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Background: The description of adherence based on medication refill histories relies on the estimation of continuous medication availability (CMA) during an observation period. Thresholds to distinguish adherence from non-adherence typically refer to an aggregated value across the entire observation...