Redox modifications of cysteine residues regulate the cytokine activity of HMGB1
Abstract Background High mobility group box 1 (HMGB1) is a nuclear protein with extracellular inflammatory cytokine activity. It is passively released during cell death and secreted by activated cells of many lineages. HMGB1 contains three conserved redox-sensitive cysteine residues: cysteines in po...
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Main Authors: | Huan Yang (Author), Peter Lundbäck (Author), Lars Ottosson (Author), Helena Erlandsson-Harris (Author), Emilie Venereau (Author), Marco E. Bianchi (Author), Yousef Al-Abed (Author), Ulf Andersson (Author), Kevin J. Tracey (Author) |
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Format: | Book |
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BMC,
2021-06-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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