Systemic Treatment with Nicotinamide Riboside Is Protective in Two Mouse Models of Retinal Ganglion Cell Damage

• Main Authors: Xian Zhang (Author), Nan Zhang (Author), Micah A. Chrenek (Author), Preston E. Girardot (Author), Jiaxing Wang (Author), Jana T. Sellers (Author), Eldon E. Geisert (Author), Charles Brenner (Author), John M. Nickerson (Author), Jeffrey H. Boatright (Author), Ying Li (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glaucoma etiology often includes retinal ganglion cell (RGC) death associated with elevated intraocular pressure (IOP). However, even when IOP is managed well, disease can progress. It is thus important to develop therapeutic approaches that directly protect RGCs in an IOP-independent manner. Compro...