Pimozide Inhibits the Human Prostate Cancer Cells Through the Generation of Reactive Oxygen Species

• Glavni autori: Ukjin Kim (Autor), C-Yoon Kim (Autor), Ji Min Lee (Autor), Bokyeong Ryu (Autor), Jin Kim (Autor), Changsoo Shin (Autor), Jae-Hak Park (Autor)
• Format: Knjiga
• Izdano: Frontiers Media S.A., 2020-01-01T00:00:00Z.
• Teme: article
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The United States Food and Drug Administration-approved antipsychotic drug, pimozide, has anticancer activities. However, the role of reactive oxygen species (ROS) in its effect on prostate cancer is not well-known. We examined cell proliferation, colony formation, migration, ROS production, and the...