Dually Cross-Linked Core-Shell Structure Nanohydrogel with Redox-Responsive Degradability for Intracellular Delivery

• Main Authors: Siyuan Deng (Author), Maria Rosa Gigliobianco (Author), Emin Mijit (Author), Marco Minicucci (Author), Manuela Cortese (Author), Barbara Campisi (Author), Dario Voinovich (Author), Michela Battistelli (Author), Sara Salucci (Author), Pietro Gobbi (Author), Giulio Lupidi (Author), Giorgia Zambito (Author), Laura Mezzanotte (Author), Roberta Censi (Author), Piera Di Martino (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A redox-responsive nanocarrier is a promising strategy for the intracellular drug release because it protects the payload, prevents its undesirable leakage during extracellular transport, and favors site-specific drug delivery. In this study, we developed a novel redox responsive core-shell structur...