Stimulation of Autophagy by Dapagliflozin Mitigates Cadmium-Induced Testicular Dysfunction in Rats: The Role of AMPK/mTOR and SIRT1/Nrf2/HO-1 Pathways

• المؤلفون الرئيسيون: Hany H. Arab (مؤلف), Ebtehal Mohammad Fikry (مؤلف), Shuruq E. Alsufyani (مؤلف), Ahmed M. Ashour (مؤلف), Azza A. K. El-Sheikh (مؤلف), Hany W. Darwish (مؤلف), Abdullah M. Al-Hossaini (مؤلف), Muhammed A. Saad (مؤلف), Muhammad Y. Al-Shorbagy (مؤلف), Ahmed H. Eid (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2023-07-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Cadmium (Cd) is a widespread environmental pollutant that triggers testicular dysfunction. Dapagliflozin is a selective sodium-glucose co-transporter-2 inhibitor with notable antioxidant and anti-apoptotic features. It has shown marked cardio-, reno-, hepato-, and neuroprotective effects. Yet, its e...