ube3d, a New Gene Associated with Age-Related Macular Degeneration, Induces Functional Changes in Both In Vivo and In Vitro Studies

• Main Authors: Huika Xia (Author), Qi Zhang (Author), Yan Shen (Author), Yujing Bai (Author), Xiaoyun Ma (Author), Bo Zhang (Author), Yun Qi (Author), Jingjing Zhang (Author), Qinrui Hu (Author), Wei Du (Author), Li Zhu (Author), Peng Zhou (Author), Bin Wang (Author), Hui Xu (Author), Lvzhen Huang (Author), Xiaoxin Li (Author)
• Format: Book
• Published: Elsevier, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neovascular age-related macular degeneration (AMD) is characterized by the formation of choroidal neovascularization, which is responsible for more than 80% of cases of severe vision loss. Ubiquitin protein ligase E3D (UBE3D) gene missense has been proven to be associated with neovascular AMD in the...