Intra-Amniotic Delivery of CRMP4 siRNA Improves Mesenchymal Stem Cell Therapy in a Rat Spina Bifida Model

• Main Authors: Xiaowei Wei (Author), Songying Cao (Author), Wei Ma (Author), Chaonan Zhang (Author), Hui Gu (Author), Dan Liu (Author), Wenting Luo (Author), Yuzuo Bai (Author), Weilin Wang (Author), Zhengwei Yuan (Author)
• Format: Book
• Published: Elsevier, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neural tube defects (NTDs) result in prenatal mortality and lifelong morbidity, and available treatments have limited efficacy. We previously suggested that prenatal bone marrow-derived mesenchymal stem cell (BMSC) transplantation could treat neuron deficiency in NTD rats; however, BMSC-based therap...