Voriconazole Pharmacokinetics in Critically Ill Patients and Extracorporeal Membrane Oxygenation Support: A Retrospective Comparative Case-Control Study

• Egile Nagusiak: Mar Ronda (Egilea), Josep Manuel Llop-Talaveron (Egilea), MariPaz Fuset (Egilea), Elisabet Leiva (Egilea), Evelyn Shaw (Egilea), Victor Daniel Gumucio-Sanguino (Egilea), Yolanda Diez (Egilea), Helena Colom (Egilea), Raul Rigo-Bonnin (Egilea), Mireia Puig-Asensio (Egilea), Jordi Carratalà (Egilea), Ariadna Padullés (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2023-06-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Voriconazole, an antifungal agent, displays high intra- and inter-individual variability. The predictive pharmacokinetic (PK) index requires a minimum plasma concentration (C_min) in patient serum of between 1-5.5 mg/L. It is common to encounter fungal infections in patients un...