Voriconazole Pharmacokinetics in Critically Ill Patients and Extracorporeal Membrane Oxygenation Support: A Retrospective Comparative Case-Control Study

• Main Authors: Mar Ronda (Author), Josep Manuel Llop-Talaveron (Author), MariPaz Fuset (Author), Elisabet Leiva (Author), Evelyn Shaw (Author), Victor Daniel Gumucio-Sanguino (Author), Yolanda Diez (Author), Helena Colom (Author), Raul Rigo-Bonnin (Author), Mireia Puig-Asensio (Author), Jordi Carratalà (Author), Ariadna Padullés (Author)
• Format: Book
• Published: MDPI AG, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Voriconazole, an antifungal agent, displays high intra- and inter-individual variability. The predictive pharmacokinetic (PK) index requires a minimum plasma concentration (C_min) in patient serum of between 1-5.5 mg/L. It is common to encounter fungal infections in patients un...